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Target
Quinone oxidoreductase
Ligand
BDBM50204914
Substrate
n/a
Meas. Tech.
ChEMBL_428131 (CHEMBL915768)
IC50
>400000±n/a nM
Citation
 Krick, A; Kehraus, S; Gerhäuser, C; Klimo, K; Nieger, M; Maier, A; Fiebig, HH; Atodiresei, I; Raabe, G; Fleischhauer, J; König, GM Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis. J Nat Prod 70:353-60 (2007) [PubMed]  Article 
Target
Name:
Quinone oxidoreductase
Synonyms:
Cryz | QOR_MOUSE
Type:
PROTEIN
Mol. Mass.:
35275.21
Organism:
Mus musculus
Description:
ChEMBL_428131
Residue:
331
Sequence:
MATGQKLMRAIRVFEFGGPEVLKLQSDVVVPVPQSHQVLIKVHACGVNPVETYIRSGAYSRKPALPYTPGSDVAGIIESVGDKVSAFKKGDRVFCYSTVSGGYAEFALAADDTIYPLPETLNFRQGAALGIPYFTACRALFHSARARAGESVLVHGASGGVGLATCQIARAHGLKVLGTAGSEEGKKLVLQNGAHEVFNHKEANYIDKIKMSVGDKDKGVDVIIEMLANENLSNDLKLLSHGGRVVVVGCRGPIEINPRDTMAKETSIIGVSLSSSTKEEFQQFAGLLQAGIEKGWVKPVIGSEYPLEKAAQAHEDIIHGSGKTGKMILLL
  
Inhibitor
Name:
BDBM50204914
Synonyms:
(1S,3S,4S,4a,9aS)-1,3,4,8-tetrahydroxy-4a,6-dimethyl-1,2,3,4,4a,9a-hexahydro-9H-xanthen-9-one | CHEMBL373944
Type:
Small organic molecule
Emp. Form.:
C15H18O6
Mol. Mass.:
294.2998
SMILES:
Cc1cc(O)c2C(=O)[C@H]3[C@@H](O)C[C@H](O)[C@H](O)[C@@]3(C)Oc2c1
Structure:
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