Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM50206646
Substrate
n/a
Meas. Tech.
ChEMBL_438448 (CHEMBL887548)
Ki
15000±n/a nM
Citation
 Lee, YS; Nyberg, J; Moye, S; Agnes, RS; Davis, P; Ma, SW; Lai, J; Porreca, F; Vardanyan, R; Hruby, VJ Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors. Bioorg Med Chem Lett 17:2161-5 (2007) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50206646
Synonyms:
(S)-N-(1-(2-amino-2-(2,3-dihydro-1H-inden-2-yl)acetyl)piperidin-4-yl)-N-phenylpropionamide | CHEMBL230415
Type:
Small organic molecule
Emp. Form.:
C25H31N3O2
Mol. Mass.:
405.5325
SMILES:
CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)C1Cc2ccccc2C1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: