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Target
Baculoviral IAP repeat-containing protein 5
Ligand
BDBM50209186
Substrate
n/a
Meas. Tech.
ChEMBL_443470 (CHEMBL893728)
Kd
5000±n/a nM
Citation
 Wendt, MD; Sun, C; Kunzer, A; Sauer, D; Sarris, K; Hoff, E; Yu, L; Nettesheim, DG; Chen, J; Jin, S; Comess, KM; Fan, Y; Anderson, SN; Isaac, B; Olejniczak, ET; Hajduk, PJ; Rosenberg, SH; Elmore, SW Discovery of a novel small molecule binding site of human survivin. Bioorg Med Chem Lett 17:3122-9 (2007) [PubMed]  Article 
Target
Name:
Baculoviral IAP repeat-containing protein 5
Synonyms:
API4 | Apoptosis inhibitor 4 | Apoptosis inhibitor survivin | BIRC5 | BIRC5_HUMAN | IAP4
Type:
PROTEIN
Mol. Mass.:
16386.52
Organism:
Homo sapiens (Human)
Description:
ChEMBL_443470
Residue:
142
Sequence:
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD
  
Inhibitor
Name:
BDBM50209186
Synonyms:
1-(4-chlorophenyl)-1H-indole | CHEMBL233218
Type:
Small organic molecule
Emp. Form.:
C14H10ClN
Mol. Mass.:
227.689
SMILES:
Clc1ccc(cc1)-n1ccc2ccccc12
Structure:
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