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TargetBaculoviral IAP repeat-containing protein 5
LigandBDBM50209184
Substrate/Competitorn/a
Meas. Tech.ChEMBL_443470
Kd 7560±n/a nM
Citation Wendt, MDSun, CKunzer, ASauer, DSarris, KHoff, EYu, LNettesheim, DGChen, JJin, SComess, KMFan, YAnderson, SNIsaac, BOlejniczak, ETHajduk, PJRosenberg, SHElmore, SW Discovery of a novel small molecule binding site of human survivin. Bioorg Med Chem Lett17:3122-9 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Baculoviral IAP repeat-containing protein 5
Name:Baculoviral IAP repeat-containing protein 5
Synonyms:Apoptosis inhibitor 4 | Apoptosis inhibitor survivin
Type:PROTEIN
Mol. Mass.:16386.52
Organism:Homo sapiens
Description:ChEMBL_443470
Residue:142
Sequence:
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFC
FKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNK
KKEFEETAKKVRRAIEQLAAMD
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BDBM50209184
NameBDBM50209184
Synonyms:4-(2,5-dichlorophenyl)-6-(2-hydroxy-5-isobutylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile | CHEMBL399196
TypeSmall organic molecule
Emp. Form.C22H18Cl2N2O2
Mol. Mass.413.297
SMILESCC(C)Cc1ccc(O)c(c1)-c1cc(-c2cc(Cl)ccc2Cl)c(C#N)c(=O)[nH]1
Structure
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