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TargetBaculoviral IAP repeat-containing protein 5
LigandBDBM50209201
Substrate/Competitorn/a
Meas. Tech.ChEMBL_443470
Kd 48±n/a nM
Citation Wendt, MDSun, CKunzer, ASauer, DSarris, KHoff, EYu, LNettesheim, DGChen, JJin, SComess, KMFan, YAnderson, SNIsaac, BOlejniczak, ETHajduk, PJRosenberg, SHElmore, SW Discovery of a novel small molecule binding site of human survivin. Bioorg Med Chem Lett17:3122-9 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Baculoviral IAP repeat-containing protein 5
Name:Baculoviral IAP repeat-containing protein 5
Synonyms:Apoptosis inhibitor 4 | Apoptosis inhibitor survivin
Type:PROTEIN
Mol. Mass.:16386.52
Organism:Homo sapiens
Description:ChEMBL_443470
Residue:142
Sequence:
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFC
FKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNK
KKEFEETAKKVRRAIEQLAAMD
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BDBM50209201
NameBDBM50209201
Synonyms:CHEMBL233848 | N-(5-chloro-3-(4-(2-chloro-5-(trifluoromethyl)phenyl)-5-cyano-6-oxo-1,6-dihydropyridin-2-yl)-2-hydroxybenzyl)-1-acetylpiperidine-4-carboxamide
TypeSmall organic molecule
Emp. Form.C28H23Cl2F3N4O4
Mol. Mass.607.408
SMILESCC(=O)N1CCC(CC1)C(=O)NCc1cc(Cl)cc(c1O)-c1cc(-c2cc(ccc2Cl)C(F)(F)F)c(C#N)c(=O)[nH]1
Structure
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