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Target
Adenosine receptor A1
Ligand
BDBM50211680
Substrate
n/a
Meas. Tech.
ChEMBL_436387 (CHEMBL904695)
Ki
>10000±n/a nM
Citation
 Vidal, B; Nueda, A; Esteve, C; Domenech, T; Benito, S; Reinoso, RF; Pont, M; Calbet, M; López, R; Cadavid, MI; Loza, MI; Cárdenas, A; Godessart, N; Beleta, J; Warrellow, G; Ryder, H Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist. J Med Chem 50:2732-6 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50211680
Synonyms:
4'-(2-furyl)-N-pyrimidin-5-yl-4,5'-bipyrimidin-2'-amine | CHEMBL225972
Type:
Small organic molecule
Emp. Form.:
C16H11N7O
Mol. Mass.:
317.3048
SMILES:
N(c1cncnc1)c1ncc(-c2ccncn2)c(n1)-c1ccco1
Structure:
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