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Target
Malonyl-CoA decarboxylase, mitochondrial
Ligand
BDBM50202815
Substrate
n/a
Meas. Tech.
ChEMBL_459062 (CHEMBL925154)
IC50
242±n/a nM
Citation
 Patel, MR; Talele, TT 3D-QSAR studies on malonyl coenzyme A decarboxylase inhibitors. Bioorg Med Chem 15:4470-81 (2007) [PubMed]  Article 
Target
Name:
Malonyl-CoA decarboxylase, mitochondrial
Synonyms:
DCMC_HUMAN | MLYCD | Malonyl-CoA decarboxylase
Type:
PROTEIN
Mol. Mass.:
55018.37
Organism:
Homo sapiens (Human)
Description:
ChEMBL_665404
Residue:
493
Sequence:
MRGFGPGLTARRLLPLRLPPRPPGPRLASGQAAGALERAMDELLRRAVPPTPAYELREKTPAPAEGQCADFVSFYGGLAETAQRAELLGRLARGFGVDHGQVAEQSAGVLHLRQQQREAAVLLQAEDRLRYALVPRYRGLFHHISKLDGGVRFLVQLRADLLEAQALKLVEGPDVREMNGVLKGMLSEWFSSGFLNLERVTWHSPCEVLQKISEAEAVHPVKNWMDMKRRVGPYRRCYFFSHCSTPGEPLVVLHVALTGDISSNIQAIVKEHPPSETEEKNKITAAIFYSISLTQQGLQGVELGTFLIKRVVKELQREFPHLGVFSSLSPIPGFTKWLLGLLNSQTKEHGRNELFTDSECKEISEITGGPINETLKLLLSSSEWVQSEKLVRALQTPLMRLCAWYLYGEKHRGYALNPVANFHLQNGAVLWRINWMADVSLRGITGSCGLMANYRYFLEETGPNSTSYLGSKIIKASEQVLSLVAQFQKNSKL
  
Inhibitor
Name:
BDBM50202815
Synonyms:
CHEMBL246029 | N-(4-methylpentan-2-yl)-4-(2,2,2-trifluoroacetyl)benzamide
Type:
Small organic molecule
Emp. Form.:
C15H18F3NO2
Mol. Mass.:
301.3041
SMILES:
CC(C)CC(C)NC(=O)c1ccc(cc1)C(=O)C(F)(F)F |w:4.4|
Structure:
Search PDB for entries with ligand similarity: