Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50213155
Substrate
n/a
Meas. Tech.
ChEMBL_447433 (CHEMBL896457)
Ki
1.7±n/a nM
Citation
 Worm, K; Zhou, QJ; Stabley, GJ; DeHaven, RN; Dolle, RE Biaryl cannabinoid mimetics--synthesis and structure-activity relationship. Bioorg Med Chem Lett 17:3652-6 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50213155
Synonyms:
4-(1,1-dimethyl-heptyl)-2',6'-dimethyl-biphenyl-2-ol | CHEMBL232410
Type:
Small organic molecule
Emp. Form.:
C23H32O
Mol. Mass.:
324.4996
SMILES:
CCCCCCC(C)(C)c1ccc(c(O)c1)-c1c(C)cccc1C |(13.06,-4.96,;13.83,-6.29,;13.06,-7.62,;13.83,-8.96,;13.06,-10.29,;13.83,-11.63,;13.06,-12.96,;14.38,-13.73,;12.29,-14.3,;11.72,-12.19,;11.71,-10.64,;10.38,-9.88,;9.05,-10.65,;9.05,-12.19,;7.71,-12.96,;10.38,-12.96,;7.72,-9.88,;7.72,-8.34,;9.06,-7.57,;6.39,-7.57,;5.06,-8.34,;5.06,-9.89,;6.39,-10.65,;6.4,-12.19,)|
Structure:
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