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Target
D(1A) dopamine receptor
Ligand
BDBM50214407
Substrate
n/a
Meas. Tech.
ChEMBL_439027 (CHEMBL889373)
Kd
1200±n/a nM
Citation
 Vendrell, M; Angulo, E; Casadó, V; Lluis, C; Franco, R; Albericio, F; Royo, M Novel ergopeptides as dual ligands for adenosine and dopamine receptors. J Med Chem 50:3062-9 (2007) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50214407
Synonyms:
(6aR,9R)-N-((S)-1-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-3-methyl-1-oxobutan-2-ylamino)-4-cyclohexyl-1-oxobutan-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide | CHEMBL226639
Type:
Small organic molecule
Emp. Form.:
C36H50N6O4
Mol. Mass.:
630.82
SMILES:
CC(C)[C@H](NC(=O)[C@H](CCC1CCCCC1)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)N1CCC[C@H]1C(N)=O |c:35|
Structure:
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