Reaction Details Report a problem with these data
Target
Albumin
Ligand
BDBM50219743
Substrate
n/a
Meas. Tech.
ChEMBL_457248 (CHEMBL941734)
Kd
4400±n/a nM
Citation
 Stiff, CM; Zhong, M; Sarver, RW; Gao, H; Ho, AM; Sweeney, MT; Zurenko, GE; Romero, DL Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors. Bioorg Med Chem Lett 17:5479-82 (2007) [PubMed]  Article 
Target
Name:
Albumin
Synonyms:
ALB | ALBU_HUMAN | Serum albumin
Type:
PROTEIN
Mol. Mass.:
69362.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1509401
Residue:
609
Sequence:
MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
  
Inhibitor
Name:
BDBM50219743
Synonyms:
2-(3-(morpholinosulfonyl)benzamido)-5-nitrobenzoic acid | CHEMBL395703
Type:
Small organic molecule
Emp. Form.:
C18H17N3O8S
Mol. Mass.:
435.408
SMILES:
OC(=O)c1cc(ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCOCC1)[N+]([O-])=O
Structure:
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