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TargetAGTR1
LigandBDBM50221304
Substrate/Competitorn/a
Meas. Tech.ChEMBL_457557
Ki>10000±n/a nM
Citation Murugaiah, AMWallinder, CMahalingam, AKWu, XWan, YPlouffe, BBotros, MKarlén, AHallberg, MGallo-Payet, NAlterman, M Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system. Bioorg Med Chem15:7166-83 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
AGTR1
Name:Angiotensin II receptor (AT-1) type-1
Synonyms:ANGIOTENSIN AT1 | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | Type-1A angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40910.53
Organism:RAT
Description:ANGIOTENSIN AT1 AGTR1 RAT::P25095
Residue:359
Sequence:
MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
Blast this sequence in BindingDB or PDB
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BDBM50221304
NameBDBM50221304
Synonyms:CHEMBL246667 | N-butyloxycarbonyl-3-[4-(N-benzylcarbamoylmethyl)phenyl]-5-iso-butylthiophene-2-sulfonamide
TypeSmall organic molecule
Emp. Form.C28H34N2O5S2
Mol. Mass.542.71
SMILESCCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CC(=O)NCc2ccccc2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a