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Target
D(3) dopamine receptor
Ligand
BDBM50221673
Substrate
n/a
Meas. Tech.
ChEMBL_449683 (CHEMBL898787)
Ki
0.31±n/a nM
Citation
 Rodriguez Loaiza, P; Löber, S; Hübner, H; Gmeiner, P Click chemistry based solid phase supported synthesis of dopaminergic phenylacetylenes. Bioorg Med Chem 15:7248-57 (2007) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50221673
Synonyms:
CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-4-ethynylbenzamide
Type:
Small organic molecule
Emp. Form.:
C23H25Cl2N3O
Mol. Mass.:
430.37
SMILES:
Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)C#C)CC2)c1Cl
Structure:
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