Reaction Details Report a problem with these data
Target
Somatostatin receptor type 5
Ligand
BDBM50227129
Substrate
n/a
Meas. Tech.
ChEMBL_452345 (CHEMBL902582)
Ki
20±n/a nM
Citation
 Guba, W; Green, LG; Martin, RE; Roche, O; Kratochwil, N; Mauser, H; Bissantz, C; Christ, A; Stahl, M From astemizole to a novel hit series of small-molecule somatostatin 5 receptor antagonists via GPCR affinity profiling. J Med Chem 50:6295-8 (2007) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 5
Synonyms:
SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5)
Type:
Enzyme
Mol. Mass.:
39218.02
Organism:
Homo sapiens (Human)
Description:
P35346
Residue:
364
Sequence:
MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
  
Inhibitor
Name:
BDBM50227129
Synonyms:
CHEMBL241329 | N-(1-(4-chloro-3-ethoxybenzyl)piperidin-4-yl)-5-methylnicotinamide
Type:
Small organic molecule
Emp. Form.:
C21H26ClN3O2
Mol. Mass.:
387.903
SMILES:
CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)ccc1Cl
Structure:
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