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Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
Ligand
BDBM50228097
Substrate
n/a
Meas. Tech.
ChEMBL_452413 (CHEMBL902649)
Kd
>1860000±n/a nM
Citation
 Stebbins, JL; Zhang, Z; Chen, J; Wu, B; Emdadi, A; Williams, ME; Cashman, J; Pellecchia, M Nuclear magnetic resonance fragment-based identification of novel FKBP12 inhibitors. J Med Chem 50:6607-17 (2007) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase FKBP1A
Synonyms:
12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B
Type:
Isomerase
Mol. Mass.:
11953.09
Organism:
Homo sapiens (Human)
Description:
P62942
Residue:
108
Sequence:
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
  
Inhibitor
Name:
BDBM50228097
Synonyms:
CHEMBL236136 | N-(3,5-dimethylphenyl)piperidine-1-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C13H20N2O2S
Mol. Mass.:
268.375
SMILES:
Cc1cc(C)cc(NS(=O)(=O)N2CCCCC2)c1
Structure:
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