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Target
Autoinducer 2-binding periplasmic protein LuxP
Ligand
BDBM50234649
Substrate
n/a
Meas. Tech.
ChEMBL_462614 (CHEMBL929603)
IC50
22000±n/a nM
Citation
 Ni, N; Choudhary, G; Li, M; Wang, B Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi. Bioorg Med Chem Lett 18:1567-72 (2008) [PubMed]  Article 
Target
Name:
Autoinducer 2-binding periplasmic protein LuxP
Synonyms:
LUXP_VIBHA | luxP
Type:
PROTEIN
Mol. Mass.:
41453.75
Organism:
Vibrio harveyi
Description:
ChEMBL_1513759
Residue:
365
Sequence:
MKKALLFSLISMVGFSPASQATQVLNGYWGYQEFLDEFPEQRNLTNALSEAVRAQPVPLSKPTQRPIKISVVYPGQQVSDYWVRNIASFEKRLYKLNINYQLNQVFTRPNADIKQQSLSLMEALKSKSDYLIFTLDTTRHRKFVEHVLDSTNTKLILQNITTPVREWDKHQPFLYVGFDHAEGSRELATEFGKFFPKHTYYSVLYFSEGYISDVRGDTFIHQVNRDNNFELQSAYYTKATKQSGYDAAKASLAKHPDVDFIYACSTDVALGAVDALAELGREDIMINGWGGGSAELDAIQKGDLDITVMRMNDDTGIAMAEAIKWDLEDKPVPTVYSGDFEIVTKADSPERIEALKKRAFRYSDN
  
Inhibitor
Name:
BDBM50234649
Synonyms:
5-(2-aminoethyl)benzene-1,2,3-triol hydrochloride | CHEMBL535194
Type:
Small organic molecule
Emp. Form.:
C8H11NO3
Mol. Mass.:
169.1778
SMILES:
NCCc1cc(O)c(O)c(O)c1
Structure:
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