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Target
Protein tyrosine phosphatase type IVA 3
Ligand
BDBM50237956
Substrate
n/a
Meas. Tech.
ChEMBL_463142 (CHEMBL929054)
IC50
44700±n/a nM
Citation
 Park, H; Jung, SK; Jeong, DG; Ryu, SE; Kim, SJ Discovery of novel PRL-3 inhibitors based on the structure-based virtual screening. Bioorg Med Chem Lett 18:2250-5 (2008) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 3
Synonyms:
PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN
Type:
PROTEIN
Mol. Mass.:
19546.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461022
Residue:
173
Sequence:
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
  
Inhibitor
Name:
BDBM50237956
Synonyms:
1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-tetrazol-5-ylthio)ethanone | CHEMBL254255 | cid_1515366
Type:
Small organic molecule
Emp. Form.:
C16H14N4O4S
Mol. Mass.:
358.372
SMILES:
COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1
Structure:
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