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Target
DNA polymerase beta
Ligand
BDBM50241610
Substrate
n/a
Meas. Tech.
ChEMBL_527117 (CHEMBL975727)
IC50
7500±n/a nM
Citation
 Deng, JZ; Starck, SR; Hecht, SM bis-5-Alkylresorcinols from Panopsis rubescens that inhibit DNA polymerase beta. J Nat Prod 62:477-80 (1999) [PubMed]  Article 
Target
Name:
DNA polymerase beta
Synonyms:
DNA Polymerase beta | DPOLB_RAT | Polb
Type:
PROTEIN
Mol. Mass.:
38334.34
Organism:
Rattus norvegicus
Description:
ChEMBL_1361926
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
  
Inhibitor
Name:
BDBM50241610
Synonyms:
1,3-dihydroxy-5-[14'-(3' ',5' '-dihydroxyphenyl)-cis-4'-tetradecenyl]benzene | CHEMBL455348
Type:
Small organic molecule
Emp. Form.:
C26H36O4
Mol. Mass.:
412.5616
SMILES:
Oc1cc(O)cc(CCCCCCCCC\C=C/CCCc2cc(O)cc(O)c2)c1
Structure:
Search PDB for entries with ligand similarity: