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Target
Indoleamine 2,3-dioxygenase 1
Ligand
BDBM50241726
Substrate
n/a
Meas. Tech.
ChEMBL_527197 (CHEMBL971986)
Ki
2300±n/a nM
Citation
 Pereira, A; Vottero, E; Roberge, M; Mauk, AG; Andersen, RJ Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata. J Nat Prod 69:1496-9 (2006) [PubMed]  Article 
Target
Name:
Indoleamine 2,3-dioxygenase 1
Synonyms:
I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase
Type:
Enzyme
Mol. Mass.:
45330.80
Organism:
Homo sapiens (Human)
Description:
P14902
Residue:
403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
  
Inhibitor
Name:
BDBM50241726
Synonyms:
2-hydroxygarvin A | CHEMBL465623
Type:
Small organic molecule
Emp. Form.:
C23H26O7
Mol. Mass.:
414.4483
SMILES:
CCCc1c(C(=O)OC)c(OC)cc2cc3c(C(=O)C(C)(O)C(=O)C3(C)C)c(O)c12
Structure:
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