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Target
Na(+)/H(+) antiporter NhaA
Ligand
BDBM50010751
Substrate
n/a
Meas. Tech.
ChEMBL_533985 (CHEMBL994874)
IC50
2200±n/a nM
Citation
 Landau, M; Herz, K; Padan, E; Ben-Tal, N Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications. J Biol Chem 282:37854-63 (2007) [PubMed]  Article 
Target
Name:
Na(+)/H(+) antiporter NhaA
Synonyms:
NHAA_ECOLI | ant | nhaA
Type:
PROTEIN
Mol. Mass.:
41365.27
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_533985
Residue:
388
Sequence:
MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLETPVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALAIIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGARRTGVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMVVGILCGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV
  
Inhibitor
Name:
BDBM50010751
Synonyms:
1H,3H-Perimidin-2-ylideneamine | 2-aminoperimidine | CHEMBL311074
Type:
Small organic molecule
Emp. Form.:
C11H9N3
Mol. Mass.:
183.2093
SMILES:
Nc1nc2cccc3cccc([nH]1)c23
Structure:
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