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Target
D(2) dopamine receptor
Ligand
BDBM50264509
Substrate
n/a
Meas. Tech.
ChEMBL_534908 (CHEMBL982825)
Ki
19.1±n/a nM
Citation
 Andric, D; Roglic, G; Sukalovic, V; Soskic, V; Kostic-Rajacic, S Synthesis, binding properties and receptor docking of 4-halo-6-[2-(4-arylpiperazin-1-yl)ethyl]-1H-benzimidazoles, mixed ligands of D2 and 5-HT1A receptors. Eur J Med Chem 43:1696-705 (2008) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50264509
Synonyms:
4-Chloro-6-{2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl}-1H-benzimidazole | CHEMBL483247
Type:
Small organic molecule
Emp. Form.:
C19H20Cl2N4
Mol. Mass.:
375.295
SMILES:
Clc1ccccc1N1CCN(CCc2cc(Cl)c3nc[nH]c3c2)CC1
Structure:
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