Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50242557
Substrate
n/a
Meas. Tech.
ChEMBL_534563 (CHEMBL988124)
IC50
>10000±n/a nM
Citation
 Song, KS; Lee, SH; Chun, HJ; Kim, JY; Jung, ME; Ahn, K; Kim, SU; Kim, J; Lee, J Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands. Bioorg Med Chem 16:4035-51 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50242557
Synonyms:
4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide | CHEMBL487676
Type:
Small organic molecule
Emp. Form.:
C25H30Cl3N3O
Mol. Mass.:
494.884
SMILES:
Clc1ccc(cc1)C(N1CCN(CC1)C(=O)NC1CCCCCC1)c1ccc(Cl)cc1Cl
Structure:
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