Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50251130
Substrate
n/a
Meas. Tech.
ChEMBL_534562 (CHEMBL988123)
IC50
103±n/a nM
Citation
 Song, KS; Lee, SH; Chun, HJ; Kim, JY; Jung, ME; Ahn, K; Kim, SU; Kim, J; Lee, J Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands. Bioorg Med Chem 16:4035-51 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50251130
Synonyms:
4-((4-Bromophenyl)(2-chlorophenyl)methyl)-Ncyclohexylpiperazine-1-carboxamide | CHEMBL464872
Type:
Small organic molecule
Emp. Form.:
C24H29BrClN3O
Mol. Mass.:
490.864
SMILES:
Clc1ccccc1C(N1CCN(CC1)C(=O)NC1CCCCC1)c1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: