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Target
Thyrotropin-releasing hormone receptor
Ligand
BDBM50261333
Substrate
n/a
Meas. Tech.
ChEMBL_532304 (CHEMBL973227)
IC50
400000±n/a nM
Citation
 Carroll, AR; Lamb, J; Moni, R; Hooper, JN; Quinn, RJ Spongian diterpenes with thyrotropin releasing hormone receptor 2 binding affinity from Spongia sp. J Nat Prod 71:884-6 (2008) [PubMed]  Article 
Target
Name:
Thyrotropin-releasing hormone receptor
Synonyms:
Thyrotropin-releasing hormone receptor 2
Type:
PROTEIN
Mol. Mass.:
39044.21
Organism:
Rattus norvegicus
Description:
ChEMBL_532304
Residue:
352
Sequence:
MDGPSNVSLIHGDTTLGLPEYKVVSVFLVLLVCTLGIVGNAMVILVVLTSRDMHTPTNCYLVSLALADLLVLLAAGLPNVSDSLVGHWIYGRAGCLGITYFQYLGINVSSFSILAFTVERYIAICHPLRAQTVCTVARAKRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVPRGLYLPIYLLDFAVFFIGPLLVTLVLYGLIGRILFQSPLSQEAWQKERQPHGQSEAAPGNCSRAKSSRKQATRMLAVVVLLFAVLWTPYRTLVLLNSFVAQPFLDPWVLLFCRTCVYTNSAVNPVVYSLMSQKFRAAFLKLCWCRAAGPQRRAARVLTSNYSAAQETSEGTEKM
  
Inhibitor
Name:
BDBM50261333
Synonyms:
19,20-Diacetoxyspongia-13(16),14-diene | CHEMBL466560
Type:
Small organic molecule
Emp. Form.:
C24H34O5
Mol. Mass.:
402.5238
SMILES:
CC(=O)OC[C@@]1(C)CCC[C@@]2(COC(C)=O)[C@H]1CC[C@]1(C)[C@@H]2CCc2cocc12 |r|
Structure:
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