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TargetThyrotropin-releasing hormone receptor 2
LigandBDBM50261332
Substrate/Competitorn/a
Meas. Tech.ChEMBL_532304
IC50 70000±n/a nM
Citation Carroll, ARLamb, JMoni, RHooper, JNQuinn, RJ Spongian diterpenes with thyrotropin releasing hormone receptor 2 binding affinity from Spongia sp. J Nat Prod71:884-6 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thyrotropin-releasing hormone receptor 2
Name:Thyrotropin-releasing hormone receptor 2
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:39044.21
Organism:Rattus norvegicus
Description:ChEMBL_532304
Residue:352
Sequence:
MDGPSNVSLIHGDTTLGLPEYKVVSVFLVLLVCTLGIVGNAMVILVVLTSRDMHTPTNCY
LVSLALADLLVLLAAGLPNVSDSLVGHWIYGRAGCLGITYFQYLGINVSSFSILAFTVER
YIAICHPLRAQTVCTVARAKRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVPRG
LYLPIYLLDFAVFFIGPLLVTLVLYGLIGRILFQSPLSQEAWQKERQPHGQSEAAPGNCS
RAKSSRKQATRMLAVVVLLFAVLWTPYRTLVLLNSFVAQPFLDPWVLLFCRTCVYTNSAV
NPVVYSLMSQKFRAAFLKLCWCRAAGPQRRAARVLTSNYSAAQETSEGTEKM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50261332
NameBDBM50261332
Synonyms:19-Acetoxy-20-hydroxyspongia-13(16),14-diene | CHEMBL468803
TypeSmall organic molecule
Emp. Form.C22H32O4
Mol. Mass.360.4871
SMILESCC(=O)OC[C@@]1(C)CCC[C@@]2(CO)[C@H]1CC[C@]1(C)[C@@H]2CCc2cocc12 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a