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TargetMatrix metalloproteinase-7 (MMP7)
LigandBDBM50260799
Substrate/Competitorn/a
Meas. Tech.ChEMBL_552274
Ki 602±n/a nM
Citation Subramaniam, RHaldar, MKTobwala, SGanguly, BSrivastava, DKMallik, S Novel bis-(arylsulfonamide) hydroxamate-based selective MMP inhibitors. Bioorg Med Chem Lett18:3333-7 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase-7 (MMP7)
Name:Matrix metalloproteinase 7
Synonyms:Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7)
Type:Enzyme
Mol. Mass.:29681.54
Organism:Homo sapiens (Human)
Description:P09237
Residue:267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50260799
NameBDBM50260799
Synonyms:CHEMBL497962 | N-hydroxy-2,3-bis(3-(trifluoromethyl)phenylsulfonamido)propanamide
TypeSmall organic molecule
Emp. Form.C17H15F6N3O6S2
Mol. Mass.535.438
SMILESONC(=O)C(CNS(=O)(=O)c1cccc(c1)C(F)(F)F)NS(=O)(=O)c1cccc(c1)C(F)(F)F
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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