Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 3
Ligand
BDBM50271625
Substrate
n/a
Meas. Tech.
ChEMBL_556428 (CHEMBL955645)
IC50
24±n/a nM
Citation
 Fells, JI; Tsukahara, R; Fujiwara, Y; Liu, J; Perygin, DH; Osborne, DA; Tigyi, G; Parrill, AL Identification of non-lipid LPA3 antagonists by virtual screening. Bioorg Med Chem 16:6207-17 (2008) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 3
Synonyms:
EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7
Type:
Enzyme
Mol. Mass.:
40149.72
Organism:
Homo sapiens (Human)
Description:
Q9UBY5
Residue:
353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
  
Inhibitor
Name:
BDBM50271625
Synonyms:
2-(2-(2-aminoacetamido)-3-(2,4-dinitrophenylthio)propanamido)pentanedioic acid | CHEMBL482887
Type:
Small organic molecule
Emp. Form.:
C16H19N5O10S
Mol. Mass.:
473.415
SMILES:
NCC(=O)NC(CSc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O)C(=O)NC(CCC(O)=O)C(O)=O
Structure:
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