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Target
Mu-type opioid receptor
Ligand
BDBM50163909
Substrate
n/a
Meas. Tech.
ChEMBL_556845 (CHEMBL964705)
IC50
42.1±n/a nM
Citation
 Wang, CL; Yao, JL; Yu, Y; Shao, X; Cui, Y; Liu, HM; Lai, LH; Wang, R Structure-activity study of endomorphin-2 analogs with C-terminal modifications by NMR spectroscopy and molecular modeling. Bioorg Med Chem 16:6415-22 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
Mu-opioid receptor
Type:
PROTEIN
Mol. Mass.:
44729.40
Organism:
Cavia porcellus
Description:
ChEMBL_510437
Residue:
400
Sequence:
MDSGAVPGNASDCTDPFAQSTCSPAPSPGSWTNLSHLDGNLSDPCGPNRTDLVGSDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRNGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50163909
Synonyms:
CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-Phe-OMe
Type:
Small organic molecule
Emp. Form.:
C33H38N4O6
Mol. Mass.:
586.678
SMILES:
COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 |r|
Structure:
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