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Target
Adenosylhomocysteinase
Ligand
BDBM50244095
Substrate
n/a
Meas. Tech.
ChEMBL_554798 (CHEMBL953951)
Ki
20300±n/a nM
Citation
 Kojima, H; Kozaki, A; Iwata, M; Ando, T; Kitade, Y Synthesis of 3',4'-epoxynoraristeromycin analogs for molecular labeling probe of S-adenosyl-l-homocysteine hydrolase. Bioorg Med Chem 16:6575-9 (2008) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50244095
Synonyms:
9-[(10R,20S,30R,50R)-30,40-Epoxy-20-hydroxy-cyclopentan-10-yl]-9-H-2-fluoroadenine | CHEMBL451781
Type:
Small organic molecule
Emp. Form.:
C10H10FN5O2
Mol. Mass.:
251.2171
SMILES:
Nc1nc(F)nc2n(cnc12)[C@@H]1C[C@H]2O[C@H]2[C@H]1O |r|
Structure:
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