Reaction Details Report a problem with these data
Target
Type-1 angiotensin II receptor
Ligand
BDBM50251464
Substrate
n/a
Meas. Tech.
ChEMBL_488661 (CHEMBL988351)
Ki
105.6±n/a nM
Citation
 Wallinder, C; Botros, M; Rosenström, U; Guimond, MO; Beaudry, H; Nyberg, F; Gallo-Payet, N; Hallberg, A; Alterman, M Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships. Bioorg Med Chem 16:6841-9 (2008) [PubMed]  Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_PIG
Type:
PROTEIN
Mol. Mass.:
40925.99
Organism:
Sus scrofa
Description:
ChEMBL_488661
Residue:
359
Sequence:
MILNSSTEDSIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKIADIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSENGSSSTKKSAPCTEVE
  
Inhibitor
Name:
BDBM50251464
Synonyms:
CHEMBL518157 | butyl 3-(4-carbamoylphenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate
Type:
Small organic molecule
Emp. Form.:
C20H26N2O5S2
Mol. Mass.:
438.561
SMILES:
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(N)=O
Structure:
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