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Target
Bcl2-associated agonist of cell death
Ligand
BDBM50263298
Substrate
n/a
Meas. Tech.
ChEMBL_489247 (CHEMBL989994)
Kd
4000000±n/a nM
Citation
 Prakesch, M; Denisov, AY; Naim, M; Gehring, K; Arya, P The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1. Bioorg Med Chem 16:7443-9 (2008) [PubMed]  Article 
Target
Name:
Bcl2-associated agonist of cell death
Synonyms:
BAD_MOUSE | Bad | Bbc6 | GST fusion protein of Bcl2 antagonist of cell death | GST-BAD
Type:
Other Protein Type
Mol. Mass.:
22084.58
Organism:
Mus musculus (mouse)
Description:
n/a
Residue:
204
Sequence:
MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASATDRGLGPSLTEDQPGPYLAPGLLGSNIHQQGRAATNSHHGGAGAMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGLPRPKSAGTATQMRQSAGWTRIIQSWWDRNLGKGGSTPSQ
  
Inhibitor
Name:
BDBM50263298
Synonyms:
2-((2S,3R,4S)-4-(allyloxycarbonyl)-1-benzoyl-3-hydroxy-6-((2-methoxyethoxy)methoxy)-1,2,3,4-tetrahydroquinolin-2-yl)acetic acid | CHEMBL478433
Type:
Small organic molecule
Emp. Form.:
C26H30N2O9
Mol. Mass.:
514.5244
SMILES:
COCCOCOc1ccc2N([C@@H](CC(O)=O)[C@H](O)[C@@H](NC(=O)OCC=C)c2c1)C(=O)c1ccccc1 |r|
Structure:
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