Reaction Details Report a problem with these data
Target
Group IID secretory phospholipase A2
Ligand
BDBM50262804
Substrate
n/a
Meas. Tech.
ChEMBL_489273 (CHEMBL990829)
IC50
640±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Group IID secretory phospholipase A2
Synonyms:
PA2GD_MOUSE | Pla2a2 | Pla2g2d | Splash
Type:
PROTEIN
Mol. Mass.:
16175.77
Organism:
Mus musculus
Description:
ChEMBL_489273
Residue:
144
Sequence:
MRLALLCGLLLAGITATQGGLLNLNKMVTHMTGKKAFFSYWPYGCHCGLGGKGQPKDATDWCCQKHDCCYAHLKIDGCKSLTDNYKYSISQGTIQCSDNGSWCERQLCACDKEVALCLKQNLDSYNKRLRYYWRPRCKGKTPAC
  
Inhibitor
Name:
BDBM50262804
Synonyms:
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-6,7-benzoindol-4-yloxy)acetic acid | CHEMBL514705
Type:
Small organic molecule
Emp. Form.:
C27H26N2O5
Mol. Mass.:
458.5057
SMILES:
CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3ccccc3c2n1Cc1ccccc1
Structure:
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