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Target
Luciferin 4-monooxygenase
Ligand
BDBM50261810
Substrate
n/a
Meas. Tech.
ChEMBL_509645 (CHEMBL1003973)
IC50
1700±n/a nM
Citation
 Heitman, LH; van Veldhoven, JP; Zweemer, AM; Ye, K; Brussee, J; IJzerman, AP False positives in a reporter gene assay: identification and synthesis of substituted N-pyridin-2-ylbenzamides as competitive inhibitors of firefly luciferase. J Med Chem 51:4724-9 (2008) [PubMed]  Article 
Target
Name:
Luciferin 4-monooxygenase
Synonyms:
LUCI_AQULA | Luciferase
Type:
PROTEIN
Mol. Mass.:
60126.66
Organism:
Luciola lateralis
Description:
ChEMBL_786225
Residue:
548
Sequence:
MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLEKSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKGSSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRSELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAGELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREILKKPVAKM
  
Inhibitor
Name:
BDBM50261810
Synonyms:
CHEMBL510929 | N-quinolin-2-yl benzamide
Type:
Small organic molecule
Emp. Form.:
C16H12N2O
Mol. Mass.:
248.2793
SMILES:
O=C(Nc1ccc2ccccc2n1)c1ccccc1
Structure:
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