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TargetLuciferase
LigandBDBM50238208
Substrate/Competitorn/a
Meas. Tech.ChEMBL_509645
IC50 610±n/a nM
Citation Heitman, LHvan Veldhoven, JPZweemer, AMYe, KBrussee, JIJzerman, AP False positives in a reporter gene assay: identification and synthesis of substituted N-pyridin-2-ylbenzamides as competitive inhibitors of firefly luciferase. J Med Chem51:4724-9 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Luciferase
Name:Luciferase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:60126.66
Organism:Luciola lateralis
Description:ChEMBL_786225
Residue:548
Sequence:
MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLE
KSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSL
GISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKG
SSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAIL
TVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRS
ELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDK
PGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWL
HTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAG
ELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREI
LKKPVAKM
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  Blast E-value cutoff:
BDBM50238208
NameBDBM50238208
Synonyms:2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | CHEMBL405914 | cid_649849
TypeSmall organic molecule
Emp. Form.C15H16N2O3
Mol. Mass.272.2991
SMILESCOc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a