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Target
Prostatic acid phosphatase
Ligand
BDBM50272707
Substrate
n/a
Meas. Tech.
ChEMBL_510106 (CHEMBL998760)
IC50
5±n/a nM
Citation
 Vovk, AI; Mischenko, IM; Tanchuk, VY; Kachkovskii, GA; Sheiko, SY; Kolodyazhnyi, OI; Kukhar, VP Stereoselectivity of binding of alpha-(N-benzylamino)benzylphosphonic acids to prostatic acid phosphatase. Bioorg Med Chem Lett 18:4620-3 (2008) [PubMed]  Article 
Target
Name:
Prostatic acid phosphatase
Synonyms:
ACP3 | ACPP | PPAP_HUMAN | Prostatic acid phosphatase
Type:
PROTEIN
Mol. Mass.:
44563.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_158625
Residue:
386
Sequence:
MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
  
Inhibitor
Name:
BDBM50272707
Synonyms:
(R)-N-benzyl(phenyl)(phosphono)methanaminium chloride | CHEMBL454997
Type:
Small organic molecule
Emp. Form.:
C14H17NO3P
Mol. Mass.:
278.2629
SMILES:
OP(O)(=O)[C@@H]([NH2+]Cc1ccccc1)c1ccccc1 |r|
Structure:
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