Reaction Details Report a problem with these data
Target
Transcriptional activator protein TraR
Ligand
BDBM50266270
Substrate
n/a
Meas. Tech.
ChEMBL_543882 (CHEMBL1016857)
IC50
2700±n/a nM
Citation
 Geske, GD; Mattmann, ME; Blackwell, HE Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorg Med Chem Lett 18:5978-81 (2008) [PubMed]  Article 
Target
Name:
Transcriptional activator protein TraR
Synonyms:
TRAR_RHIRD | traR
Type:
PROTEIN
Mol. Mass.:
26741.83
Organism:
Rhizobium radiobacter
Description:
ChEMBL_765233
Residue:
234
Sequence:
MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQSTYFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKTANGFMSMFTMASDKPVIDLDREIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
  
Inhibitor
Name:
BDBM50266270
Synonyms:
(S)-2-(4-fluorophenoxy)-N-(2-oxotetrahydrofuran-3-yl)acetamide | CHEMBL498921
Type:
Small organic molecule
Emp. Form.:
C12H12FNO4
Mol. Mass.:
253.2264
SMILES:
Fc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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