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Target
Group 10 secretory phospholipase A2
Ligand
BDBM50274389
Substrate
n/a
Meas. Tech.
ChEMBL_537138 (CHEMBL989798)
IC50
>1600±n/a nM
Citation
 Oslund, RC; Cermak, N; Verlinde, CL; Gelb, MH Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA. Bioorg Med Chem Lett 18:5415-9 (2008) [PubMed]  Article 
Target
Name:
Group 10 secretory phospholipase A2
Synonyms:
Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10
Type:
PROTEIN
Mol. Mass.:
18153.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1442449
Residue:
165
Sequence:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
  
Inhibitor
Name:
BDBM50274389
Synonyms:
1-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)dodecan-1-one | CHEMBL485443
Type:
Small organic molecule
Emp. Form.:
C21H32O5
Mol. Mass.:
364.4758
SMILES:
CCCCCCCCCCCC(=O)c1c(O)c(C)c(O)c(C(C)=O)c1O
Structure:
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