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Target
Histidine kinase 3
Ligand
BDBM50274505
Substrate
n/a
Meas. Tech.
ChEMBL_537151 (CHEMBL989811)
EC50
19000±n/a nM
Citation
 Zatloukal, M; Gemrotová, M; Dolezal, K; Havlícek, L; Spíchal, L; Strnad, M Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase. Bioorg Med Chem 16:9268-75 (2008) [PubMed]  Article 
Target
Name:
Histidine kinase 3
Synonyms:
AHK3 | AHK3_ARATH | Histidine kinase | ORE12
Type:
PROTEIN
Mol. Mass.:
116381.97
Organism:
Arabidopsis thaliana
Description:
ChEMBL_537151
Residue:
1036
Sequence:
MSLFHVLGFGVKIGHLFWMLCCWFVSWFVDNGIEDKSGLLVGSVGDLEKTKMTTLKKKNKMWFWNKISSSGLKIPSFSYQFLGSVKFNKAWWRKLVVVWVVFWVLVSIWTFWYFSSQAMEKRKETLASMCDERARMLQDQFNVSMNHVQAMSILISTFHHGKIPSAIDQRTFSEYTDRTSFERPLTSGVAYAMRVLHSEREEFERQQGWTIRKMYSLEQNPVHKDDYDLEALEPSPVQEEYAPVIFAQDTVSHVVSLDMLSGKEDRENVLRARSSGKGVLTAPFPLIKTNRLGVILTFAVYKRDLPSNATPKERIEATNGYLGGVFDIESLVENLLQQLASKQTILVNVYDITNHSQPISMYGTNVSADGLERVSPLIFGDPLRKHEMRCRFKQKPPWPVLSMVTSFGILVIALLVAHIIHATVSRIHKVEEDCDKMKQLKKKAEAADVAKSQFLATVSHEIRTPMNGVLGMLHMLMDTELDVTQQDYVRTAQASGKALVSLINEVLDQAKIESGKLELEEVRFDLRGILDDVLSLFSSKSQQKGVELAVYISDRVPDMLIGDPGRFRQILTNLMGNSIKFTEKGHIFVTVHLVDELFESIDGETASSPESTLSGLPVADRQRSWENFKAFSSNGHRSFEPSPPDINLIVSVEDTGVGIPVEAQSRIFTPFMQVGPSISRTHGGTGIGLSISKCLVGLMKGEIGFSSTPKVGSTFTFTAVFSNGMQPAERKNDNNQPIFSEFRGMKAVVVDHRPARAKVSWYHFQRLGIRVEVVPRVEQALHYLKIGTTTVNMILIEQEIWNREADDFIKKLQKDPLFLSPKLILLANSVESSISEALCTGIDPPIVIVKPLRASMLAATLQRGLGIGIREPPQHKGPPALILRNLLLGRKILIVDDNNVNLRVAAGALKKYGADVVCAESGIKAISLLKPPHEFDACFMDIQMPEMDGFEATRRIRDMEEEMNKRIKNGEALIVENGNKTSWHLPVLAMTADVIQATHEECLKCGMDGYVSKPFEAEQLYREVSRFFNSPSDTES
  
Inhibitor
Name:
BDBM50274505
Synonyms:
2-(2-chloro-9H-purin-6-ylamino)phenol | CHEMBL485562
Type:
Small organic molecule
Emp. Form.:
C11H8ClN5O
Mol. Mass.:
261.667
SMILES:
Oc1ccccc1Nc1nc(Cl)nc2nc[nH]c12
Structure:
Search PDB for entries with ligand similarity: