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Target
Histidine kinase 3
Ligand
BDBM50267036
Substrate
n/a
Meas. Tech.
ChEMBL_537151 (CHEMBL989811)
EC50
700±n/a nM
Citation
 Zatloukal, M; Gemrotová, M; Dolezal, K; Havlícek, L; Spíchal, L; Strnad, M Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase. Bioorg Med Chem 16:9268-75 (2008) [PubMed]  Article 
Target
Name:
Histidine kinase 3
Synonyms:
AHK3 | AHK3_ARATH | Histidine kinase | ORE12
Type:
PROTEIN
Mol. Mass.:
116381.97
Organism:
Arabidopsis thaliana
Description:
ChEMBL_537151
Residue:
1036
Sequence:
MSLFHVLGFGVKIGHLFWMLCCWFVSWFVDNGIEDKSGLLVGSVGDLEKTKMTTLKKKNKMWFWNKISSSGLKIPSFSYQFLGSVKFNKAWWRKLVVVWVVFWVLVSIWTFWYFSSQAMEKRKETLASMCDERARMLQDQFNVSMNHVQAMSILISTFHHGKIPSAIDQRTFSEYTDRTSFERPLTSGVAYAMRVLHSEREEFERQQGWTIRKMYSLEQNPVHKDDYDLEALEPSPVQEEYAPVIFAQDTVSHVVSLDMLSGKEDRENVLRARSSGKGVLTAPFPLIKTNRLGVILTFAVYKRDLPSNATPKERIEATNGYLGGVFDIESLVENLLQQLASKQTILVNVYDITNHSQPISMYGTNVSADGLERVSPLIFGDPLRKHEMRCRFKQKPPWPVLSMVTSFGILVIALLVAHIIHATVSRIHKVEEDCDKMKQLKKKAEAADVAKSQFLATVSHEIRTPMNGVLGMLHMLMDTELDVTQQDYVRTAQASGKALVSLINEVLDQAKIESGKLELEEVRFDLRGILDDVLSLFSSKSQQKGVELAVYISDRVPDMLIGDPGRFRQILTNLMGNSIKFTEKGHIFVTVHLVDELFESIDGETASSPESTLSGLPVADRQRSWENFKAFSSNGHRSFEPSPPDINLIVSVEDTGVGIPVEAQSRIFTPFMQVGPSISRTHGGTGIGLSISKCLVGLMKGEIGFSSTPKVGSTFTFTAVFSNGMQPAERKNDNNQPIFSEFRGMKAVVVDHRPARAKVSWYHFQRLGIRVEVVPRVEQALHYLKIGTTTVNMILIEQEIWNREADDFIKKLQKDPLFLSPKLILLANSVESSISEALCTGIDPPIVIVKPLRASMLAATLQRGLGIGIREPPQHKGPPALILRNLLLGRKILIVDDNNVNLRVAAGALKKYGADVVCAESGIKAISLLKPPHEFDACFMDIQMPEMDGFEATRRIRDMEEEMNKRIKNGEALIVENGNKTSWHLPVLAMTADVIQATHEECLKCGMDGYVSKPFEAEQLYREVSRFFNSPSDTES
  
Inhibitor
Name:
BDBM50267036
Synonyms:
(2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol | (E)-2-methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol | (E)-2-methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol | (E)-2-methyl-4-(purin-6-ylamino)-2-buten-1-ol | (E)-zeatin | CHEMBL525239 | trans-zeatin
Type:
Small organic molecule
Emp. Form.:
C10H13N5O
Mol. Mass.:
219.2431
SMILES:
CC(CO)=CCNc1ncnc2nc[nH]c12 |w:4.4|
Structure:
Search PDB for entries with ligand similarity: