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Target
Cytokinin dehydrogenase 2
Ligand
BDBM50274590
Substrate
n/a
Meas. Tech.
ChEMBL_537152 (CHEMBL989812)
IC50
>100000±n/a nM
Citation
 Zatloukal, M; Gemrotová, M; Dolezal, K; Havlícek, L; Spíchal, L; Strnad, M Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase. Bioorg Med Chem 16:9268-75 (2008) [PubMed]  Article 
Target
Name:
Cytokinin dehydrogenase 2
Synonyms:
CKX2 | CKX2_ARATH
Type:
PROTEIN
Mol. Mass.:
55587.96
Organism:
Arabidopsis thaliana
Description:
ChEMBL_537152
Residue:
501
Sequence:
MANLRLMITLITVLMITKSSNGIKIDLPKSLNLTLSTDPSIISAASHDFGNITTVTPGGVICPSSTADISRLLQYAANGKSTFQVAARGQGHSLNGQASVSGGVIVNMTCITDVVVSKDKKYADVAAGTLWVDVLKKTAEKGVSPVSWTDYLHITVGGTLSNGGIGGQVFRNGPLVSNVLELDVITGKGEMLTCSRQLNPELFYGVLGGLGQFGIITRARIVLDHAPKRAKWFRMLYSDFTTFTKDQERLISMANDIGVDYLEGQIFLSNGVVDTSFFPPSDQSKVADLVKQHGIIYVLEVAKYYDDPNLPIISKVIDTLTKTLSYLPGFISMHDVAYFDFLNRVHVEENKLRSLGLWELPHPWLNLYVPKSRILDFHNGVVKDILLKQKSASGLALLYPTNRNKWDNRMSAMIPEIDEDVIYIIGLLQSATPKDLPEVESVNEKIIRFCKDSGIKIKQYLMHYTSKEDWIEHFGSKWDDFSKRKDLFDPKKLLSPGQDIF
  
Inhibitor
Name:
BDBM50274590
Synonyms:
2-chloro-6-(3-methoxyanilino)-9-isopropylpurine | CHEMBL510099
Type:
Small organic molecule
Emp. Form.:
C15H16ClN5O
Mol. Mass.:
317.773
SMILES:
COc1cccc(Nc2nc(Cl)nc3n(cnc23)C(C)C)c1
Structure:
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