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Target
Gag polyprotein
Ligand
BDBM50273850
Substrate
n/a
Meas. Tech.
ChEMBL_536774 (CHEMBL984568)
IC50
1500±n/a nM
Citation
 LaFrate, AL; Gunther, JR; Carlson, KE; Katzenellenbogen, JA Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor. Bioorg Med Chem 16:10075-84 (2008) [PubMed]  Article 
Target
Name:
Gag polyprotein
Synonyms:
GAG_AVIER | gag
Type:
PROTEIN
Mol. Mass.:
61664.68
Organism:
Avian erythroblastosis virus (strain ES4)
Description:
ChEMBL_536774
Residue:
555
Sequence:
REEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEMGETTVQRDAKMAPEKMATPKTVGTSCYQCGTATGCNCVTASAPPPPYVGSGLYPSLAGAGEQGQGGDTPRGAEQPRAEPGHAGQAPGPALTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPEDTRWLDGKHKRKSSQCLVKSSMSGYIPSCLDKDEQCVVCGDKATGYHYRCITCEGCKSFFRRTIQKNLHPTYSCTYDGCCVIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRKLIEENRERRRKEEMIKSLQHRPSPSAEEWELIHVVTEAHRSTNAQGSHWKQRRKFLLEDIGQSPMASMLDGDKVDLEAFSEFTKIITPAITRVVDFAKNLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLSAFNLDDTEVALLQAVLLMSSDRTGLICVDKIEKCQESYLLAFEHYINYRKHNIPHFWSKLLMKVADLRMIGAYHASRFLHMKVECPTELSPQEV
  
Inhibitor
Name:
BDBM50273850
Synonyms:
1-Chloro-3-dihydro-4-methylnaphthalene-2-carboxaldehyde guanylhydrazone | CHEMBL456393
Type:
Small organic molecule
Emp. Form.:
C13H15ClN4
Mol. Mass.:
262.738
SMILES:
[#6]-[#6]-1-[#6]-[#6](-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])=[#6](Cl)-c2ccccc-12 |w:4.3,t:9|
Structure:
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