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TargetDual specificity protein phosphatase 1
LigandBDBM50060898
Substrate/Competitorn/a
Meas. Tech.ChEMBL_565116
IC50 9370±n/a nM
Citation Cao, SMurphy, BTFoster, CLazo, JSKingston, DG Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem17:2276-81 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dual specificity protein phosphatase 1
Name:Dual specificity protein phosphatase 1
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:39372.46
Organism:Mus musculus
Description:ChEMBL_565116
Residue:367
Sequence:
MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM
GLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFF
LQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSF
LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA
IDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS
FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSP
ITTSPSC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50060898
NameBDBM50060898
Synonyms:5,8-Dihydroxy-[1,4]naphthoquinone | 5,8-dihydroxy-1,4-dihydronaphthalene-1,4-dione (7a) | 5,8-dihydroxy-1,4-naphthoquinone | CHEMBL274056 | naphthazalin
TypeSmall organic molecule
Emp. Form.C10H6O4
Mol. Mass.190.1522
SMILESOc1ccc(O)c2C(=O)C=CC(=O)c12 |c:9|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a