Reaction Details Report a problem with these data
Target
Solute carrier family 28 member 3
Ligand
BDBM50241221
Substrate
n/a
Meas. Tech.
ChEMBL_518727 (CHEMBL957102)
Ki
>100000±n/a nM
Citation
 Gupte, A; Buolamwini, JK Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors. Bioorg Med Chem Lett 19:917-21 (2009) [PubMed]  Article 
Target
Name:
Solute carrier family 28 member 3
Synonyms:
CNT3 | S28A3_HUMAN | SLC28A3
Type:
PROTEIN
Mol. Mass.:
76938.51
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1494517
Residue:
691
Sequence:
MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQSREHTNTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYKDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTFNCNGISNTF
  
Inhibitor
Name:
BDBM50241221
Synonyms:
1-(2,4-dihydroxyphenyl)ethanone | 2',4'-dihydroxyacetophenone | 4-Acetylresorcinol | CHEMBL243374
Type:
Small organic molecule
Emp. Form.:
C8H8O3
Mol. Mass.:
152.1473
SMILES:
CC(=O)c1ccc(O)cc1O
Structure:
Search PDB for entries with ligand similarity: