Reaction Details Report a problem with these data
Target
Solute carrier family 28 member 3
Ligand
BDBM23446
Substrate
n/a
Meas. Tech.
ChEMBL_518727 (CHEMBL957102)
Ki
32280±n/a nM
Citation
 Gupte, A; Buolamwini, JK Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors. Bioorg Med Chem Lett 19:917-21 (2009) [PubMed]  Article 
Target
Name:
Solute carrier family 28 member 3
Synonyms:
CNT3 | S28A3_HUMAN | SLC28A3
Type:
PROTEIN
Mol. Mass.:
76938.51
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1494517
Residue:
691
Sequence:
MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQSREHTNTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYKDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTFNCNGISNTF
  
Inhibitor
Name:
BDBM23446
Synonyms:
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one | CHEMBL45068 | Phloretin | cid_4788
Type:
Dihydrochalcone
Emp. Form.:
C15H14O5
Mol. Mass.:
274.2687
SMILES:
Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
Structure:
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