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Target
Fructose-1,6-bisphosphatase 1
Ligand
BDBM50266638
Substrate
n/a
Meas. Tech.
ChEMBL_516599 (CHEMBL988686)
IC50
150600±n/a nM
Citation
 Rudnitskaya, A; Huynh, K; Török, B; Stieglitz, K Novel heteroaromatic organofluorine inhibitors of fructose-1,6-bisphosphatase. J Med Chem 52:878-82 (2009) [PubMed]  Article 
Target
Name:
Fructose-1,6-bisphosphatase 1
Synonyms:
F16P1_MOUSE | Fbp | Fbp1 | Fbp3
Type:
PROTEIN
Mol. Mass.:
36912.07
Organism:
Mus musculus
Description:
ChEMBL_748173
Residue:
338
Sequence:
MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK
  
Inhibitor
Name:
BDBM50266638
Synonyms:
3,5-bis(4-fluorophenyl)-1-phenyl-1H-pyrazole | CHEMBL479098
Type:
Small organic molecule
Emp. Form.:
C21H14F2N2
Mol. Mass.:
332.3461
SMILES:
Fc1ccc(cc1)-c1cc(-c2ccc(F)cc2)n(n1)-c1ccccc1
Structure:
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