Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM50267099
Substrate
n/a
Meas. Tech.
ChEMBL_563763 (CHEMBL993526)
IC50
1004000±n/a nM
Citation
 Ottanà, R; Maccari, R; Ciurleo, R; Paoli, P; Jacomelli, M; Manao, G; Camici, G; Laggner, C; Langer, T 5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors. Bioorg Med Chem 17:1928-37 (2009) [PubMed]  Article 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM50267099
Synonyms:
4-[(5-Naphthalen-1-ylmethylene-4-oxo-2-phenyliminothiazolidin-3-yl)methyl] benzoic acid | CHEMBL477263
Type:
Small organic molecule
Emp. Form.:
C28H20N2O3S
Mol. Mass.:
464.535
SMILES:
OC(=O)c1ccc(CN2\C(S\C(=C/c3cccc4ccccc34)C2=O)=N\c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: