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Target
Testis-specific serine/threonine-protein kinase 1
Ligand
BDBM50279386
Substrate
n/a
Meas. Tech.
ChEMBL_545767 (CHEMBL1027662)
IC50
38700±n/a nM
Citation
 Zhang, L; Yan, Y; Liu, Z; Abliz, Z; Liu, G Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays. J Med Chem 52:4419-28 (2009) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 1
Synonyms:
SPOGA1 | SPOGA4 | STK22A | STK22D | TSSK1 | TSSK1B | TSSK1_HUMAN | Testis-specific serine/threonine-protein kinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41624.03
Organism:
Homo sapiens (Human)
Description:
gi_14042947
Residue:
367
Sequence:
MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ
  
Inhibitor
Name:
BDBM50279386
Synonyms:
5-hydroxy-8-methyl-4-propyl-7,8-dihydropyrano[3,2-g]chromene-2,6-dione | CHEMBL483974
Type:
Small organic molecule
Emp. Form.:
C16H16O5
Mol. Mass.:
288.2952
SMILES:
CCCc1cc(=O)oc2cc3OC(C)CC(=O)c3c(O)c12
Structure:
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