Reaction Details Report a problem with these data
Target
Carboxypeptidase A1
Ligand
BDBM50279945
Substrate
n/a
Meas. Tech.
ChEBML_45616
Ki
250±n/a nM
Citation
 Kim, DH; Shin, YS; Kim, KB The structural feature of S1′ subsite of carboxypeptidase A Bioorg Med Chem Lett 1:317-322 (1991)    Article 
Target
Name:
Carboxypeptidase A1
Synonyms:
CBPA1_BOVIN | CPA | CPA1 | Carboxypeptidase A | Carboxypeptidase A (CPA) | Carboxypeptidase A1 precursor
Type:
Enzyme
Mol. Mass.:
47073.90
Organism:
Bos taurus (bovine)
Description:
From Sigma-Aldrich Co.
Residue:
419
Sequence:
MQGLLILSVLLGAALGKEDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPGSPIDVRVPFPSLQAVKVFLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSRARSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYGSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTLNNLY
  
Inhibitor
Name:
BDBM50279945
Synonyms:
3-(3,4-Difluoro-phenyl)-2-mercaptomethyl-propionic acid | CHEMBL108812
Type:
Small organic molecule
Emp. Form.:
C10H10F2O2S
Mol. Mass.:
232.247
SMILES:
OC(=O)C(CS)Cc1ccc(F)c(F)c1
Structure:
Search PDB for entries with ligand similarity: