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Target
Neurotensin receptor type 1
Ligand
BDBM50280251
Substrate
n/a
Meas. Tech.
ChEBML_144290
IC50
6000±n/a nM
Citation
 Snider, RM; Pereira, DA; Longo, KP; Davidson, RE; Vinick, FJ; Laitinen, K; Genc-Sehitoglu, E; Crawley, JN UK-73,093: A non-peptide neurotensin receptor antagonist Bioorg Med Chem Lett 2:1535-1540 (1992)    Article 
Target
Name:
Neurotensin receptor type 1
Synonyms:
NT-R-1 | NTR1_MOUSE | Neurotensin 1 | Neurotensin receptor 1 | Neurotensin receptor type 1 | Ntsr | Ntsr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47237.04
Organism:
MOUSE
Description:
Neurotensin 1 NTSR1 MOUSE::A2ACT4
Residue:
424
Sequence:
MHLNSSVQQGAPSEPGAQPFPHPQFGLETMLLALSLSNGSGNSSESILEPNSNLDVNTDIYSKVLVTAVYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGLQNRSADGQHPGGLVCTPTVDTATVKVVIQVNTFMSFLFPMLIISILNTVIANKLTVMVHQAAEQGRGVCTVGTHNSLEHSTFNMSIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRRRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
  
Inhibitor
Name:
BDBM50280251
Synonyms:
4-Methyl-N-[2-(3-oxo-1-phenyl-1,3-dihydro-isobenzofuran-1-ylamino)-ethyl]-benzenesulfonamide | CHEMBL38243 | UK-73093
Type:
Small organic molecule
Emp. Form.:
C23H22N2O4S
Mol. Mass.:
422.497
SMILES:
Cc1ccc(cc1)S(=O)(=O)NCCNC1(OC(=O)c2ccccc12)c1ccccc1
Structure:
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