Reaction Details Report a problem with these data
Target
3-phosphoshikimate 1-carboxyvinyltransferase
Ligand
BDBM50281354
Substrate
n/a
Meas. Tech.
ChEMBL_64950 (CHEMBL675695)
IC50
150000±n/a nM
Citation
 Knowles, WS; Anderson, KS; Andrew, SS; Phillion, DP; Ream, JE; Johnson, KA; Sikorski, JA Synthesis & characterization of N-amino-glyphosate as a potent analog inhibitor of E. coli EPSP synthase. Bioorg Med Chem Lett 3:2863-2868 (1993)    Article 
Target
Name:
3-phosphoshikimate 1-carboxyvinyltransferase
Synonyms:
5-enolpyruvylshikimate-3-phosphate synthase | AROA_ECOLI | aroA
Type:
PROTEIN
Mol. Mass.:
46089.22
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_65087
Residue:
427
Sequence:
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
  
Inhibitor
Name:
BDBM50281354
Synonyms:
(Methyl-phosphonomethyl-amino)-acetic acid | CHEMBL97756
Type:
Small organic molecule
Emp. Form.:
C4H10NO5P
Mol. Mass.:
183.0997
SMILES:
CN(CC(O)=O)CP(O)(O)=O
Structure:
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