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Target
Amiloride-sensitive amine oxidase [copper-containing]
Ligand
BDBM50207159
Substrate
n/a
Meas. Tech.
ChEBML_53890
Ki
140±n/a nM
Citation
 Griffith, RK; DiPietro, RA Synthesis of 4(5)-imidazolyl allylamines and propargylamines as inhibitors of diamine oxidase Bioorg Med Chem Lett 3:353-356 (1993)    Article 
Target
Name:
Amiloride-sensitive amine oxidase [copper-containing]
Synonyms:
ABP | ABP1 | AOC1 | AOC1_HUMAN | Amiloride-binding protein | DAO | DAO1 | Diamine oxidase | Diamine oxidase (DAO) | Histaminase | KAO | Kidney amine oxidase
Type:
Protein
Mol. Mass.:
85387.64
Organism:
Homo sapiens (Human)
Description:
P19801
Residue:
751
Sequence:
MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
  
Inhibitor
Name:
BDBM50207159
Synonyms:
2-aminoguanidine | 2-azanylguanidine | AMINOGUANIDINE | CHEMBL225304 | Guanyl hydrazine | Imino semicarbazide | Monoaminoguanidine | hydrazinecarboximidamide
Type:
Small organic molecule
Emp. Form.:
CH6N4
Mol. Mass.:
74.0851
SMILES:
NNC(N)=N
Structure:
Search PDB for entries with ligand similarity: